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It is also noteworthy in our study that, while the NP with the lowest nicotine content (6 mg On!) had one of the highest C max values (17.5 ng/mL) and the highest nicotine bioavailability, the subjective effects scores (liking and intent to use again) were lowest for this NP, whereas there were no major differences among the other four NP products with differing nicotine contents

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