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(2025, March 11)

Cigarette smoke inhibits ciliary activity of the bronchial epithelium and phagocytic activity of macrophages in the alveoli, resulting in decreased clearance of foreign material and bacteria from the lung, which leads to increased infection and tissue destruction

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Model validation and performance assessment We also used previously developed validation methods [2123] to select the best-performing model among a number of different plausible models