In October 1926, Henry Ford made a big decision
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Moreover, elevated GSH levels can protect tumor cells by reducing the cytotoxic effects of several chemotherapy drugs, including cisplatin, doxorubicin, melphalan, and paclitaxel, ultimately leading to drug resistance [17]
Observed Side Effects (From Clinical Trials) In the Lancet 2021 Phase 2 trial (n=706), at the highest 4.5 mg/week dose, 88% of participants reported at least one side effect and 63% reported a GI-specific event
Incorporation of 6-thioguanine nucleotides into DNA during maintenance therapy of childhood acute lymphoblastic leukemia-the influence of thiopurine methyltransferase genotypes