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In early T cell receptor activation, intracellular calcium signaling is dependent on G6PD and dual oxidase 1 (DUOX1) enzyme activity, which work in concert to facilitate NADP/NADPH cycling (58)

Its structure incorporates specific amino acid substitutions to enhance solubility and prevent fibril formation, along with the addition of a C18 fatty diacid moiety via a linker

Cortex 3 , 373386 (1993)