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Treatment of alemtuzumab leads to significant depletion of T and B lymphocytes, natural killer (NK) cells, dendritic cells, granulocytes, and monocytes via several mechanisms (152)

In CKD, urine albumin levels increase and, as a result, the ratio of albumin to creatinine increases

For example, increasing the level of mercaptan in T cells can lead to T cell-mediated arthritis in mice after collagen immunization (Gelderman et al., 2007)

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Targeting apoptosis in cancer therapy