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doi: 10.1038/s41419-024-06435-w 51 DoLKLeeHMHaYSLeeCHKimJ

Temperatures above 86 degrees Fahrenheit exceed the approved storage range for every semaglutide product on the market

Methodology Study design and participants In this cross-sectional, study, we obtained approval for the research proposal from the universitys research committee and received ethical clearance from the Yasuj University of Medical Sciences (Ethic code: IR.YUMS.REC.1404.056

It further outlines techniques to measure lipid peroxidation (MDA, 4-HNE), protein carbonylation (DNPH method, 3-nitrotyrosine via LCMS), DNA damage (8-OHdG detection by HPLCMS/MS), and inflammation markers (RT-qPCR for cytokines)