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Patients who need a lower-cost option may begin with oral medications and transition to GLP-1 therapy later if financially feasible

This technique typically results in less pain, a shorter hospital stay, and a faster recovery

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The high costs present significant reimbursement issues, especially when healthcare systems around the world are facing budget pressures due to increasing use of GLP-1 agonists worldwide, where global spending on this therapeutic area is projected to exceed USD 42 billion per year in 2025

Six months of ALC supplementation (1,500 mgs/2 xs daily) significantly increased sensory nerve density and reduced neuropathic pain in HIV patients with retroviral drug-induced nerve damage