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She notes that some plans require step therapy (proof that a lower-cost treatment, such as metformin, has been tried first), a recent A1c test, or documentation that the patient has received lifestyle counseling to help manage their diabetes

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Within the combination options, incretin-based therapies will play a relevant role, given that most patients with MASH have T2DM or obesity, conditions in which these are already commonly used

Given these dynamics, obesity drugs were simply not an exciting space for investments

The details of these findings may differ depending on a patients specific health conditions