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The SIRT6 expression is downregulated in HG-induced db/db mice and the glomerular podocytes treated by HG, accompanied by the increased glomerular volume, compensatory renal tubule hypertrophy, inflammatory cell infiltration, and the increased mesangial matrix

Several recent in vitro and animal studies have shown that ferroptosis inducers, chemotherapy, and immunotherapy can synergistically affect ovarian cancer [35,41]

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