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Most clients describe minimal discomfort, often less than they expected

Diabetes Care 24:16401645 Vilsbll T, Krarup T, Deacon CF, Madsbad S, Holst JJ (2001) Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients

Some researchers also keep a marker on hand to label the vial with the reconstitution date

Similar content being viewed by others Background Many patients with type 2 diabetes (T2D) eventually need a greater potency of injectable glucose-lowering agents (GLAs) because T2D is a progressive disease [1, 2]

The practical rule: never refreeze a reconstituted vial that has been thawed and partially used unless it has been aliquoted into single-use fractions first