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These recruited monocyte/macrophage populations, together with tissue-resident macrophages, amplify the local inflammatory response by releasing additional inflammatory mediators, cytokines, and growth factors into the pancreatic microenvironment

Common side effects include nausea, fatigue, and bloating

Furthermore, GLS2, but not GLS1, is a target of p53, a tumor suppressor protein

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Lixisenatide is structurally related to exendin-4 (six lysine residues have been added to the C terminus, and one proline in the C-terminal region has been deleted) but can be administered once daily (QD)