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Although the mechanisms through which metformin exerts glucose-lowering actions are incompletely understood, treatment of diabetic patients with metformin reduced hepatic glucose production, primarily via decreased gluconeogenesis [2]

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[DOI] [PubMed] [Google Scholar] 29.Chen L., Lee M.J., Li H., Yang C.S

However, only few therapeutic studies have evaluated the effectiveness and safety of antidiabetic drugs and the impact of the treatment of DM on morbidity and mortality in patients with liver cirrhosis

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