No Glp1r transcripts were identified in VTA dopamine neurons
If semaglutide-associated depression does happen, the vortioxetinebupropion pairing used here, with vortioxetine deliberately held at 10 mg to allow for the CYP2D6 interaction, is a pharmacologically sensible option that brought remission twice in this patient
In contrast, a 2024 Scientific Reports analysis found a small increased risk of anxiety and suicidal behavior in people with obesity on GLP-1 drugs and a higher apparent rate of major depression
Peptides have been used in medicines for about 100 years, and some peptides are made into oral supplements and skin and hair care products for anti-aging, muscle growth, and fat loss benefits
Spending at fast-food, coffee shops, and other limited-service spots falls by about 8 percent