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Glutathione is a tripeptide (a group of three amino acids joined by peptide bonds) and includes the amino acids glutamine, glycine, and cysteine

Compared to HCs, 103 metabolites were elevated but 123 were declined in the R group ( Figure 2F )

They work by inhibiting tyrosinase activity, which reduces melanin production, and by shifting melanin production from darker eumelanin to lighter pheomelanin

Highlights The manuscript explores the role of the gut-brain-skin axis in alopecia, highlighting the link between gut microbiota imbalance and hair loss

In this case, adding a small amount of T3 to standard T4 treatment may be beneficial, but dose adjustment is a very sensitive process and is done mostly with symptom control