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Note that reconstituted injectable GHK-Cu can be used topically, but topical copper peptide products formulated for skin application may include additional ingredients optimizing penetration and stability that simple water reconstitution doesn't provide

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Because Crohns causes inflammation of the intestinal tract, it not only interferes with B12 absorption but can cause more severe symptoms like arthritis, skin problems, fevers, rectal bleeding, and abdominal pain

Although more research is needed to solidify these findings, evidence published by the American Academy of Pain Medicine points to the efficacy of B12 as an adjunctive treatment alongside lidocaine for pain management