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Although the first weekly doses are small so your body can get used to it, many patients lose weight in the first week of taking semaglutide especially if they are making lifestyle changes

At Set Point Medical Weight Loss Clinic, transitioning from Semaglutide GLP-1 to tirzepatide is a key step in your weight loss journey

Tirzepatide (Mounjaro, Zepbound), a dual GIP/GLP-1 receptor agonist, reports injection site reaction rates of approximately 1.7-2.2% in its FDA prescribing information, similar to semaglutide

What else you should know If you don't lose 4% of your weight after 16 weeks of taking liraglutide, your doctor may tell you to stop taking it because it's unlikely to work for you

Interestingly, when switching from Liraglutide to Semaglutide, administered at 0.5 and 0.75 mg once a week, respectively, there was a noticeable decrease in weight