These findings align with broader evidence that GLP-1 receptor agonists reduce cardiovascular disease risk, particularly stroke, in other high-risk populations
233 Sodium-glucose cotransporter-2 (SGLT2) inhibitors are commonly used for type 2 diabetes treatment, and in recent years, SGLT2 inhibitors canagliflozin has been shown to suppress IL-6 and IL-1 levels and MPO enzyme activity in the colon of UC rats by downregulating the expression of NF-B p65, thereby reducing colonic inflammatory cell infiltration and oxidative stress
Clinical Evidence on GLP-1 and Hypertension Multiple randomized controlled trials have documented blood pressure reductions in GLP-1 users
Disruption of the intestinal barrier and intestinal mucosal inflammation in UC is often coupled with the decrease in the number of bacterial species traditionally associated with beneficial effects on the host in the gut [45]
Aus Proglucagon entstehen in Pankreas, Darm und Gehirn Glucagon und glucagonhnliche Peptide (GLP1, GLP2) - mit breitem Aktionsradius: So frdert GLP1 Insulinempfindlichkeit und Glucoseaufnahme im Muskel, Knochenbildung und Herzfunktion, und schtzt das Nervengewebe