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doi: 10.3389/fcell.2021.703218 156 YangJCZhaoMChernikovaDArias-JayoNZhouYSituJet al

Notably, these results agree with a recent review confirming the safety and effectiveness of the ALA and GLA combination for improving DPN [133]

This, in turn, leads to reduced brain tryptophan concentration, decreased 5-HT levels, and diminished 5-HT receptor binding, which may underlie the 5-HT system dysfunction, impaired neurotransmission, and negative cognitive effects observed in SZ

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