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Over the following weeks, most people report gradual improvement in tendon, ligament, and muscle recovery and in joint discomfort from training or everyday wear

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Endpoints focused on endoscopic healing will be required to demonstrate an additive benefit beyond weight loss

Panagaki T, Michael M, Holscher C

In phase 3 trials, lecanemab and donanemab slowed clinical decline in early Alzheimers by roughly a quarter to a third over eighteen months, with a known risk of amyloid-related brain swelling and small bleeds