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doi: 10.3389/fendo.2012.00141 46 WeiYMojsovS

It is a fixed-dose, extended-release combination of sitagliptin (a dipeptidyl peptidase-4 inhibitor) and metformin hydrochloride (a biguanide)

Conclusions Once-weekly cagrilintide-semaglutide (at a dose of 2.4 mg each) resulted in a significantly lower body weight than placebo in adults with obesity and type 2 diabetes

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While several biomarkers may represent strong potential candidates as early indicators of liver injury, the existing literature is limited by studies that have relatively small sample numbers and relatively sparse sampling strategies