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Not drinking enough water or a lack of essential electrolytes can also result in dry and hard-to-pass stool

doi: 10.3389/fnut.2025.1612479 8 SunGJXuFJiaoXYYinY

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As Talpos's investigation recounts, the idea traces to 1975, when as a second-year medical student he reasoned that the stomach must produce a natural anti-stress healing substance, which he named Substancija Boe Pomozi, or "Substance God Help Me." His team gathered stomach fluid from clinics and pig slaughterhouses, screened it across years, and in 1989 reported a protein from which they identified the peptide they named BPC-157