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Trehalose protects against oxidative stress by regulating the Keap1Nrf2 and autophagy pathways

The assay monitors autoxidation reactions initiated by radicals, measuring inhibition through methods like oxygen uptake and induction periods in the presence of tocopherols

References Franziska H, Gnter H, Mathias B et al (2024) Definition and diagnosis of Parkinsons disease: guideline Parkinsons disease of the German Society of Neurology

METAOD006: A Phase IIb, randomized, double-blind, placebo-controlled study to assess the efficacy (reduction in body weight), safety and tolerability of 24 weeks treatment with different doses of AOD9604 tablets (0.25 mg, 0.5 mg, 1 mg, or placebo) in 502 obese adults

Generation of DDX3X stable cell line HEK293 Flp-In cells, pOG44 and pcDNA5/FRT plasmids were generously provided by Dr