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This oxidative death is characterized by an accumulation of lipid peroxides that disrupts the integrity of the plasma membrane, ultimately leading to ferroptotic death [44, 47, 61]
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On day 6, mice randomly assigned to the PTSD group were subjected to the SPS protocol, which consisted of three sequential stressors
As shown in Section Riboflavin Ameliorates Oxidative Stress, Mitochondrial Dysfunction, and Neuroinflammation, riboflavin has antioxidant properties and upregulates antioxidant enzymes especially SOD, also, supplementation with riboflavin will elevate the intra-mitochondrial FAD levels compensating for the decline in the capacity to assemble of dysfunctional mitochondrial complexes
Frias JP, Deenadayalan S, Erichsen L, et al
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