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[DOI] [PubMed] [Google Scholar] 115.Clapper M.L., Szarka C.E., Pfeiffer G.R., Graham T.A., Balshem A.M., Litwin S., Goosenberg E.B., Frucht H., Engstrom P.F

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Causes of MCAS include: Chronic bacterial infections, such as Lyme disease, Babesia, and Bartonella Chronic viral infections, such as Epstein-Barr Virus and Long COVID Mold illness & fungal infections Heavy metals Environmental toxins, such as herbicides & pesticides SIBO and leaky gut syndrome Allergens food and environmental Genetically predisposed Additionally, certain triggers cause mast cells to degranulate and release mediators in susceptible individuals