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Top-line results showed that on average, people who switched to orforglipron from semaglutide had a superior percent maintenance of body weight reduction, showing that subjects held onto their earlier weight loss compared to those who previously reached a body weight plateau

Ballinger SW, Patterson C, Knight-Lozano CA, Burow DL, Conklin CA, Hu Z, Reuf J, Horaist C, Lebovitz R, Hunter GC, McIntyre K, Runge MS