In a phase II dose-finding trial involving patients with obesity but without type 2 diabetes, once-daily subcutaneous semaglutide produced significantly greater weight loss than both placebo and liraglutide
Of note, the extent of the demonstrated beneficial effect on recovery of muscle function and integrity is considerable, and involves the transection- (15, 37) crush- (16, 17) lesion of striated muscle, and healing impairment induced by systemic corticosteroid application (16), as well as function impairment induced by centrally acting agents (74, 75)
Write down your questions before each appointment: How can I maintain or build more muscle while on this medication
Accessibility & cost : Its availability in the UK remains uncertain, and likely expensive much like current GLP-1 options
Demand is so great that Ozempic and Wegovy are on the FDAs drug-shortage list