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Due to its critical function in renewing nerve fibers and mending nerve damage, vitamin B12 is essential for maintaining healthy nerves

BBB blood-brain-barrier HGF hepatocyte growth factor neurotrophic factors are large proteins that lack significant BBB penetrability

One group received daily vitamin C (1000 milligrams) plus vitamin E (335 milligrams), while the comparison group took placebo tablets

Research has shown that p53 can suppress the expression of SLC7A11, a key component of the cystine/glutamate antiporter (X c system), leading to the inhibition of cystine uptake and sensitization to ferroptosis

Only 11.2% of participants stopped the trial due to side effects, and the discontinuation rate dropped significantly after week 24, suggesting those who make it through the early phase generally tolerate it well long-term