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For a huge swath of the US population, about 40%, there now exists a therapeutic approach outside of surgery, known as GLP-1 agonists, that could improve the weight loss journey

Compounds in this category are studied in preclinical research models examining the incretin axis GLP-1, GIP, glucagon, and amylin receptor pharmacology

The Lancet Diabetes & Endocrinology , 12(8), 545-561

Abstract To enable survival in adverse conditions, cancer cells undergo global metabolic adaptations

Furthermore, because our study was conducted in normal aging rats, without diabetes or other pathological conditions such as Alzheimers disease, we aimed to use the lowest effective dose to minimize potential adverse effects while still achieving beneficial effects on the brain