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Shown are membrane-bound hemichromes (panel A), complement C3c fragment (panel B) and autologous IgG (panel C) in ring-infected and non-infected GR-deficient RBCs from the index patient, brother (individual 2) and sister (individual 3) of index patient, and from normal GR-sufficient controls

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Sekhon LH, Gupta S, Kim Y, Agarwal A

High-fat diet (HFD)-induced diabetic mice exhibited more severe renal damage, including higher renal injury scores, elevated levels of serum BUN (blood urea nitrogen), CCr (creatinine clearance rate) and Cysc (cystatin C), oxidative stress and ferroptosis

Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice