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B12 supplements contain only cobalamin, typically in doses from 50 to 1,000+ micrograms, used for confirmed or suspected B12 deficiency

The restrictions inadvertently fueled a dangerous gray market, where patients turned to unregulated online vendors for research use only peptides, which carry a high risk of contamination, incorrect dosing, and impurities

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Researchers must verify peptide purity via HPLC or mass spectrometry before use, as degraded samples produce inconsistent results that waste experimental resources and confound data interpretation