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Natural GLP-1 is broken down within minutes by an enzyme called DPP-4

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Proc Natl Acad Sci 115(17):43174319 Ashraf SA, Khan MA, Awadelkarim AM, Tajuddin S, Ahmad MF, Hussain T (2019) GC-MS analysis of commercially available Allium sativum and Trigonella foenum-graecum essential oils and their antimicrobial activities

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This has led to therapeutic efforts to induce tolerance to these epitopes (251, 252)

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