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The safety and tolerability profile of retatrutide was generally consistent with other incretin-based therapies such as semaglutide (Ozempic/Wegovy) and tirzepatide (Mounjaro)

1956;11 doi: 10.1093/geronj/11.3.298

By understanding whether your genetic predispositions suggest higher or lower GLP-1 pathway activation, you and your provider can proactively plan dosing strategies and side effect mitigationpotentially reducing the intensity of early gastrointestinal symptoms like sulfur burps

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