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The importance of Fc-dependent antibody effector functions for protection against yellow fever virus in mice was indicated by the greater efficacy of an IgG2a antibody (which is a potent activator of effector functions) than an IgG1 antibody (a poor activator of effector functions) with the same Fab region 166

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This is why research on GLP-1 function in metabolism has expanded rapidly in recent years, influencing fields ranging from obesity science to diabetes care