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February Feb 27: In one of the more closely watched decisions of the first quarter of 2024, the FDA rejected Minerva Neurosciences roluperidone, which had been proposed to treat the negative symptoms of schizophrenia
In addition to the lack of results, I also experienced some digestive issues while taking the pills
The SURMOUNT-2 and STEP-2 trials both showed this pattern 3,4
Key Mechanisms of Action: Stimulates Lipolysis (Fat Breakdown) AOD-9604 activates beta-3 adrenergic receptors in adipose (fat) tissue, triggering the release of stored fatty acids for energy use
Researchers study its potential to enhance the export of triglycerides from the liver by promoting VLDL synthesis and secretion, thereby reducing intracellular lipid droplet accumulation
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