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The scRNA-seq data were aligned to the Ensembl_v105_mus_musculus and row count matrices were imported to the R package Seurat V3.1.1

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Additionally, cysteine desulfhydrase (dcyD/CDS, CdsH, LCD/DES1) are enzymes that produces H 2 S from cysteine and have been described in diverse intestinal pathogens such as Salmonella typhi [80,159], Mycobacterium tuberculosis, [31,80,159] Helicobacter pylori [160], and the protozoan Leishmania major, [161] as well as various oral microorganisms, including Streptococcus, Prevotella, and Fusobacterium [109,159,[161], [162], [163], [164], [165], [166], [167]]