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When tirzepatide added GIP to GLP-1, it produced roughly 5-7 percentage points more weight loss than GLP-1 alone in the SURMOUNT-1 trial (Jepsen et al., NEJM 2022)

272 Senescent HSCs may secrete proinflammatory factors, chemokines, and proteases, which affect themselves and other cells, disrupting the homeostasis of the bone marrow microenvironment

Its also important to clear up a common misconception between compounded and generic medications