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3.2.3 Immune rewiring and chronic inflammation Chronic inflammation is a key pathological consequence of dysregulated ECM remodeling in hypothyroidism-associated MAFLD and serves as a major driver of hepatic fibrogenesis

Oxidized Low-Density Lipoprotein Accumulation Suppresses Glycolysis and Attenuates the Macrophage Inflammatory Response by Diverting Transcription from the HIF-1 to the Nrf2 Pathway

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The activated Akt phosphorylates and inactivates Bad, a pro-apoptotic member of the bcl-2 family, therefore promoting cell survival (17)

10.3390/antiox11010040 10.3390/antiox11010040 [DOI] [PMC free article] [PubMed] [Google Scholar] Sang Y, Cao F, Li W et al (2020) Bioinspired construction of a nanozyme-based H2O2 homeostasis disruptor for intensive chemodynamic therapy