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Chronic irritation may lead to inflammation and swelling of the vocal folds, resulting in: Hoarseness Raspy voice Voice fatigue Reduced vocal range Long-term smoking is also linked to Reinkes edema, a condition in which fluid accumulates within the vocal cords, causing a deepened or rough-sounding voice

Cigarette smoke decreases pulmonary dendritic cells and impacts antiviral immune responsiveness

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91, and was among the largest declines reported by a food, beverage and tobacco producer last year, with results hurt by sharper declines for the Asia Pacific, Latin America and East and Africa regions