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Targeted intra-articular delivery of DEX can be achieved by using small positively charged nanoparticles bound to DEX to form electrostatic interactions between the cationic particle and the anionic cartilage matrix

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doi: 10.1007/s11154-013-9261-9

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But the hop extract group showed approximately sixfold increases in CCK levels, and the curve was elongated, lasting longer

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IV therapy generally does not lead to side effects

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