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Taking supplements can help to reverse the symptoms of neuropathy or reduce them to a large extent

Proceedings of the National Academy of Sciences of the United States of America 108 , 1687616882, doi:10.1073/pnas.1114228108 (2011)

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Patients with certain allele combinations may have naturally heightened receptor sensitivity, meaning standard doses trigger stronger satiety and gastric effects, including nausea

TB-500 component: 2-2.5mg twice weekly during loading phase (first 4-6 weeks), reducing to 2-2.5mg weekly during maintenance