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The mRNA levels of the antioxidant gene sod2 were decreased in all three recombinant cell lines compared to the control cell line before IBDV infection, with the most pronounced decrease in the mRNA levels of the sod2 gene in the recombinant GSS-M cell line (Fig

Tumorigenesis-associated metabolic reprogramming affects the genomic status by regulating the enzymes for epigenetic modifications, which commonly utilize key metabolites as either substrates or allosteric regulators (Etchegaray and Mostoslavsky, 2016

that may overlap with one of the peaks of GS-NEM

Additionally, the bidirectional relation between neuroinflammation and neuronal injury requires further investigation

doi: 10.1016/j.cell.2008.01.046 91 YuPFHuangYXuCLLinLYHanYYSunWHet al