dr gordon glutathione J. Freeman, PhD - Dana-Farber Cancer Institute Dr. Gordon, MD| Sports Medicine

NADPH contributes to recycling in oxidized antioxidant systems involving glutathione, thioredoxins, glutaredoxins, and peroxiredoxins and maintains another reactive oxygen species (ROS)-detoxifying enzyme, catalase, in its active form, suggesting that the homeostatic level of G6PD-derived NADPH determines the rate of oxidative damage [8]

Metal chelation Redox-active metal ions, such as free iron and copper, can induce oxidative damage by catalyzing reactions that generate highly reactive free radicals (20)

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Campbell MK

Maus M, Lpez-Polo V, Mateo L, Lafarga M, Aguilera M, De Lama E, et al