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Consequently, the direct regulation of transporters and enzymes within metabolic pathways, as well as the indirect regulation of Gln metabolism through the modulation of associated oncogenes and ncRNAs, may represent promising avenues for future cancer therapies

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However, investigation of these factors in preclinical studies is limited due to the time and expense of generating transgenic mice and the variability of the currently available rodent models 20

The X-ray diffraction data for PGRMC1 crystals were collected at SPring-8 BL41XU and processed with XDS 56

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