Although ligand-receptor pathways are often thought of as linear paths from engagement to transcription/translation, many studies show that enhanced oxidative potential can augment or suppress signaling pathways, including those related to MUC5AC, while more recently, oxidatively driven epigenetic effects on gene transcription have also been reported (2932)
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Astrocytes are particularly important as they are capable of producing large amounts of GSH and cysteine, both of which are exported to support neurons in the CNS
d - h , The indicated siRNAs were introduced into A549 cells ( d )
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