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This reduction in calorie intake, and subsequent weight loss, is believed to be caused by a decrease in appetite and cravings and a reduction in cravings for high-fat foods

However, since early 2025, in the United Kingdom, people who meet certain BMI criteria and have at least one weight-related co-morbidity have been able to access semaglutide ( Wegovy ) and tirzepatide ( Mounjaro ) for weight management