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Sikiric et al., 2020b) is focused on the particular skin wound therapy, incisional/excisional wound (Seiwerth et al., 1997), deep burns (Mikus et al., 2001), diabetic ulcer (Tkalecevic et al., 2007), alkali burns (Huang et al., 2015), and healing of various other tissue types (Staresinic et al., 2003

Little degradation (apparent t1/2 about 10 h) of DSIP to major metabolites, tryptophan (trp) and des-trp DSIP, occurred over the time of the diffusion experiments

Lambert et al

Effects on gene expression Transcriptomic studies in cells exposed to GHK-Cu have reported broad changes in gene expression affecting genes involved in collagen and matrix synthesis, antioxidant defense (including superoxide dismutase, catalase, and others), DNA repair, immune signaling, and cellular metabolism

You can expect some redness, tightness, and maybe even a little swelling