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doi: 10.3389/fphar.2014.00151 Received 27 May 2014 Accepted 10 June 2014 Published 01 July 2014 Volume 5 - 2014 Edited by Alfonso Pompella, Universit di Pisa, Italy Reviewed by Richard Eugene Frye, Childrens Hospital Boston/Harvard Univerity, USA
Opioid-Induced Hyperalgesia (OIH) occurs when an opioid analgesic paradoxically causes an increase in pain, or an increase in sensitivity to pain
TRT comes in many forms including oral, topical, and most commonly, injectable