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High nuclear GSH concentrations are vital since increase in total GSH is necessary for the cells to progress from the G1- (with low GSH levels) to the S-phase

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The central role of glutathione in the pathophysiology of human disease, 2007 GSH Mitochondrial Transport glutathione and mitochondrial GSH can be transported to mitochondrial matrix by different carriers, particularly the 2-oxoglutarate carrier (OGC) and the dicarboxylate carrier (DIC), located in the mitochondrial inner membrane