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Glucagon like peptide-1 protects b-cells against apoptosis by increasing the activity of an IGF-2/IGF-1 receptor autocrine loop

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The clinical evidence base for GLP-1 therapy keeps expanding into new indication categories cardiovascular risk reduction, potential Alzheimer's benefit, heart failure management, sleep apnea, and kidney disease protection are all active investigation areas

Arai T, Atsukawa M, Tsubota A, et al

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