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Skin Conditions: Acne : Moderate and severe acne can cause post-inflammatory hyperpigmentation, resulting in dark spots or marks

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Individuals taking high-dose B12 supplementswhether oral, sublingual, or intramuscular injectionsmay develop elevated serum levels, particularly if supplementation exceeds physiological requirements

Lancet 367 , 10871100 (2006)

A published case report [46] in a 61 year old man with Parkinsons disease utilized a multi-faceted protocol consisting of a gluten-free diet, along with medications, certain dietary supplements (such as N-acetyl-cysteine and Silybum ), and glutathione injections (1400 mg) administered twice or three times weekly also reported symptom improvement